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1 keywords

CATH Domain 1picA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.505 SHC Adaptor Protein
Homologous Superfamily 3.30.505.10 SH2 domain

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Phosphatidylinositol 3-kinase regulatory subunit alpha

Enzyme Information

UniProtKB Entries (1)

P27986
P85A_HUMAN
Homo sapiens
Phosphatidylinositol 3-kinase regulatory subunit alpha

PDB Structure

PDB 1PIC
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Structure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3-kinase.
Breeze, A.L., Kara, B.V., Barratt, D.G., Anderson, M., Smith, J.C., Luke, R.W., Best, J.R., Cartlidge, S.A.
EMBO J.
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