CATH Domain 1pfjA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	General transcription factor IIH subunit 1

Enzyme Information

UniProtKB Entries (1)

TF2H1_HUMAN

Homo sapiens

General transcription factor IIH subunit 1

PDB Structure

PDB	1PFJ
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	TFIIH contains a PH domain involved in DNA nucleotide excision repair. Gervais, V., Lamour, V., Jawhari, A., Frindel, F., Wasielewski, E., Dubaele, S., Egly, J.M., Thierry, J.C., Kieffer, B., Poterszman, A. Nat.Struct.Mol.Biol.