CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.167 | Regulator of G-protein Signalling 4; domain 2 |
|
1.10.167.10 | Regulator of G-protein Signalling 4, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Regulator of G-protein Signalling 4, domain 2 |
| Functional Family |
Enzyme Information
| 2.7.11.15 |
[Beta-adrenergic-receptor] kinase.
based on mapping to UniProt P21146
ATP + [beta-adrenergic receptor] = ADP + [beta-adrenergic receptor] phosphate.
-!- Acts on the agonist-occupied form of the receptor; also phosphorylates rhodopsin, but more slowly. -!- Does not act on casein or histones. -!- Inhibited by Zn(2+) and digitonin but is unaffected by cyclic-AMP (cf. EC 2.7.11.14 and EC 2.7.11.16). -!- Formerly EC 2.7.1.126.
|
UniProtKB Entries (1)
| P63212 |
GBG2_BOVIN
Bos taurus
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
|
PDB Structure
| PDB | 1OMW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Spodoptera |
| Primary Citation |
Keeping G proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and G-Beta-Gamma
Science
|
