CATH Domain 1nskU00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.141	Nucleoside diphosphate kinase-like domain

Domain Context

CATH Clusters

Superfamily	Nucleoside diphosphate kinase-like domain
Functional Family	Nucleoside diphosphate kinase B

Enzyme Information

2.7.4.6	Nucleoside-diphosphate kinase. based on mapping to UniProt P22392 ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. -!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.
2.7.13.3	Histidine kinase. based on mapping to UniProt P22392 ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. -!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.

UniProtKB Entries (1)

NDKB_HUMAN

Homo sapiens

Nucleoside diphosphate kinase B

PDB Structure

PDB	1NSK
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The crystal structure of a human nucleoside diphosphate kinase, NM23-H2. Webb, P.A., Perisic, O., Mendola, C.E., Backer, J.M., Williams, R.L. J.Mol.Biol.