CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.60 | Lipoxygenase-1 |
|
2.60.60.20 | PLAT/LH2 domain |
Domain Context
CATH Clusters
| Superfamily | PLAT/LH2 domain |
| Functional Family | Triacylglycerol lipase |
Enzyme Information
| 3.1.1.3 |
Triacylglycerol lipase.
based on mapping to UniProt P16233
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.
|
UniProtKB Entries (2)
| P02703 |
COL_PIG
Sus scrofa
Colipase
|
| P16233 |
LIPP_HUMAN
Homo sapiens
Pancreatic triacylglycerol lipase
|
PDB Structure
| PDB | 1LPB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The 2.46 A resolution structure of the pancreatic lipase-colipase complex inhibited by a C11 alkyl phosphonate.
Biochemistry
|
