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CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.1.1.3
Triacylglycerol lipase.
based on mapping to UniProt P16233
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.

UniProtKB Entries (2)

P16233
LIPP_HUMAN
Homo sapiens
Pancreatic triacylglycerol lipase
P02703
COL_PIG
Sus scrofa
Colipase

PDB Structure

PDB 1LPB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The 2.46 A resolution structure of the pancreatic lipase-colipase complex inhibited by a C11 alkyl phosphonate.
Egloff, M.P., Marguet, F., Buono, G., Verger, R., Cambillau, C., van Tilbeurgh, H.
Biochemistry
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