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1 keywords

CATH Domain 1lnsA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1820 alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.4.14.11
Xaa-Pro dipeptidyl-peptidase.
based on mapping to UniProt P22346
Hydrolyzes Xaa-Pro-|- bonds to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-|-p-nitroanilide and (sequentially) Tyr-Pro-|-Phe-Pro-|-Gly-Pro-|-Ile.
-!- EC 3.4.14.5 catalyzes a similar reaction. -!- Belongs to peptidase family S15.

UniProtKB Entries (1)

P22346
PEPX_LACLC
Lactococcus lactis subsp. cremoris
Xaa-Pro dipeptidyl-peptidase

PDB Structure

PDB 1LNS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The Structural Basis for Catalysis and Specificity of the X-prolyl dipepdidyl aminopeptidase from Lactococcus lactis
Rigolet, P., Mechin, I., Delage, M.M., Chich, J.F.
Structure
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