CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.40 | 3-Layer(aba) Sandwich |
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3.40.50 | Rossmann fold |
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3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
Superfamily | Vaccinia Virus protein VP39 |
Functional Family | Cyclopropane mycolic acid synthase 1 |
Enzyme Information
2.1.1.79 |
Cyclopropane-fatty-acyl-phospholipid synthase.
based on mapping to UniProt P9WPB7
S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl- L-homocysteine + phospholipid cyclopropane fatty acid.
-!- Adds a methylene group across the 9,10 position of a Delta(9)- olefinic acyl chain in phosphatidylethanolamine or, more slowly, phosphatidylglycerol or phosphatidylinositol forming a cyclopropane derivative (cf. EC 2.1.1.16).
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UniProtKB Entries (1)
P9WPB7 |
CMAS1_MYCTU
Mycobacterium tuberculosis H37Rv
Cyclopropane mycolic acid synthase 1
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PDB Structure
PDB | 1KP9 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis
J.Biol.Chem.
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