CATH Classification

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family SH2 domain-containing protein 1A

Enzyme Information

UniProtKB Entries (1)

Q13291
SLAF1_HUMAN
Homo sapiens
Signaling lymphocytic activation molecule

PDB Structure

PDB 1KA7
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.
Hwang, P.M., Li, C., Morra, M., Lillywhite, J., Muhandiram, D.R., Gertler, F., Terhorst, C., Kay, L.E., Pawson, T., Forman-Kay, J.D., Li, S.C.
EMBO J.
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