CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.200 | Carbonic Anhydrase II |
|
3.10.200.10 | Alpha carbonic anhydrase |
Domain Context
CATH Clusters
| Superfamily | Alpha carbonic anhydrase |
| Functional Family | Carbonic anhydrase 2 |
Enzyme Information
| 4.2.1.1 |
Carbonic anhydrase.
based on mapping to UniProt P00915
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.
|
UniProtKB Entries (1)
| P00915 |
CAH1_HUMAN
Homo sapiens
Carbonic anhydrase 1
|
PDB Structure
| PDB | 1JV0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of a zinc-activated variant of human carbonic anhydrase I, CA I Michigan 1: evidence for a second zinc binding site involving arginine coordination
Biochemistry
|
