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1 keywords

CATH Domain 1jq8A00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.90 Phospholipase A2
Homologous Superfamily 1.20.90.10 Phospholipase A2 domain

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Basic phospholipase A2 homolog

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P59071
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P59071
PA2B8_DABRR
Daboia russelii
Basic phospholipase A2 VRV-PL-VIIIa

PDB Structure

PDB 1JQ8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design of specific peptide inhibitors of phospholipase A2: structure of a complex formed between Russell's viper phospholipase A2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS).
Chandra, V., Jasti, J., Kaur, P., Dey, S., Srinivasan, A., Betzel, C.h., Singh, T.P.
ACTA CRYSTALLOGR.,SECT.D
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