CATH Domain 1jl2A00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.10	Ribonuclease H-like superfamily/Ribonuclease H

Domain Context

CATH Clusters

Superfamily	Ribonuclease H-like superfamily/Ribonuclease H
Functional Family

Enzyme Information

3.1.26.4	Ribonuclease H. based on mapping to UniProt P0A7Y4 Endonucleolytic cleavage to 5'-phosphomonoester. -!- Acts on RNA-DNA hybrids.
3.1.26.4	Ribonuclease H. based on mapping to UniProt P29253 Endonucleolytic cleavage to 5'-phosphomonoester. -!- Acts on RNA-DNA hybrids.

UniProtKB Entries (2)

P0A7Y4	RNH_ECOLI Escherichia coli K-12 Ribonuclease HI
P29253	RNH_THET8 Thermus thermophilus HB8 Ribonuclease H

PDB Structure

PDB	1JL2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Contributions of folding cores to the thermostabilities of two ribonucleases H. Robic, S., Berger, J.M., Marqusee, S. Protein Sci.