CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family |
Enzyme Information
| 1.5.1.40 |
8-hydroxy-5-deazaflavin:NADPH oxidoreductase.
based on mapping to UniProt O29370
Reduced coenzyme F420 + NADP(+) = oxidized coenzyme F420 + NADPH.
-!- The enzyme has an absolute requirement for both the 5-deazaflavin structure and the presence of an 8-hydroxy group in the substrate.
|
UniProtKB Entries (1)
| O29370 |
FNO_ARCFU
Archaeoglobus fulgidus DSM 4304
F420-dependent NADP reductase
|
PDB Structure
| PDB | 1JAX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structures of F420H2:NADP+ oxidoreductase with and without its substrates bound.
EMBO J.
|
