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1 keywords

CATH Domain 1j5oH01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Ig gamma-2B chain C region

Enzyme Information

UniProtKB Entries (1)

P03366
POL_HV1B1
Human immunodeficiency virus type 1 BH10
Gag-Pol polyprotein

PDB Structure

PDB 1J5O
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids.
Sarafianos, S.G., Das, K., Clark Jr., A.D., Ding, J., Boyer, P.L., Hughes, S.H., Arnold, E.
Proc.Natl.Acad.Sci.USA
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