CATH Domain 1iytA00

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CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.230	Amyloid A4
	4.10.230.10	Amyloidogenic glycoprotein, amyloid-beta peptide

Domain Context

CATH Clusters

Superfamily	Amyloidogenic glycoprotein, amyloid-beta peptide
Functional Family	Amyloid beta A4 protein

Enzyme Information

UniProtKB Entries (1)

A4_HUMAN

Homo sapiens

Amyloid-beta precursor protein

PDB Structure

PDB	1IYT
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Solution structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar microenvironment. Similarity with a virus fusion domain. Crescenzi, O., Tomaselli, S., Guerrini, R., Salvadori, S., D'Ursi, A.M., Temussi, P.A., Picone, D. EUR.J.BIOCHEM.