CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
Superfamily | alpha/beta hydrolase |
Functional Family | Carboxypeptidase |
Enzyme Information
3.4.16.5 |
Carboxypeptidase C.
based on mapping to UniProt P10619
Release of a C-terminal amino acid with broad specificity.
-!- Carboxypeptidases of broad specificity with optimum pH 4.5-6.0, inhibited by the action of diisopropyl fluorophosphate, and sensitive to thiol-blocking reagents. -!- This enzyme is probably also identical to lysosomal tyrosine carboxypeptidase. -!- Belongs to peptidase family S10. -!- Formerly EC 3.4.12.1, EC 3.4.12.12, EC 3.4.16.1, EC 3.4.16.3 and EC 3.4.21.13.
|
UniProtKB Entries (1)
P10619 |
PPGB_HUMAN
Homo sapiens
Lysosomal protective protein
|
PDB Structure
PDB | 1IVY |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Three-dimensional structure of the human 'protective protein': structure of the precursor form suggests a complex activation mechanism.
Structure
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