CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1350 | Trna Endonuclease; Chain: A, domain 1 |
|
3.40.1350.10 |
Domain Context
CATH Clusters
| Superfamily | 3.40.1350.10 |
| Functional Family |
Enzyme Information
| 3.1.22.4 |
Crossover junction endodeoxyribonuclease.
based on mapping to UniProt E7FHX4
Endonucleolytic cleavage at a junction such as a reciprocal single- stranded crossover between two homologous DNA duplexes (Holliday junction).
-!- The enzyme from Saccharomyces cerevisiae has no endonuclease or exonuclease activity on single-stranded or double-stranded DNA molecules that do not contain Holliday junctions.
|
UniProtKB Entries (1)
| E7FHX4 |
HJC_PYRFU
Pyrococcus furiosus DSM 3638
Holliday junction resolvase Hjc
|
PDB Structure
| PDB | 1IPI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Dissection of the regional roles of the archaeal Holliday junction resolvase Hjc by structural and mutational analyses.
J.Biol.Chem.
|