CATH Classification

Domain Context

CATH Clusters

Superfamily Rel homology domain (RHD), DNA-binding domain
Functional Family NFkB p65 transcription factor

Enzyme Information

UniProtKB Entries (2)

P25799
NFKB1_MOUSE
Mus musculus
Nuclear factor NF-kappa-B p105 subunit
P25963
IKBA_HUMAN
Homo sapiens
NF-kappa-B inhibitor alpha

PDB Structure

PDB 1IKN
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation.
Huxford, T., Huang, D.B., Malek, S., Ghosh, G.
Cell(Cambridge,Mass.)
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