CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1050 | Beta-carbonic Anhydrase; Chain A |
|
3.40.1050.10 | Carbonic anhydrase |
Domain Context
CATH Clusters
| Superfamily | Carbonic anhydrase |
| Functional Family | Carbonic anhydrase |
Enzyme Information
| 4.2.1.1 |
Carbonic anhydrase.
based on mapping to UniProt P61517
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.
|
UniProtKB Entries (1)
| P61517 |
CAN_ECOLI
Escherichia coli K-12
Carbonic anhydrase 2
|
PDB Structure
| PDB | 1I6O |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of E. coli beta-carbonic anhydrase, an enzyme with an unusual pH-dependent activity.
Protein Sci.
|
