CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.20 | Plasminogen Kringle 4 |
|
2.40.20.10 | Plasminogen Kringle 4 |
Domain Context
CATH Clusters
| Superfamily | Plasminogen Kringle 4 |
| Functional Family |
Enzyme Information
| 3.4.21.7 |
Plasmin.
based on mapping to UniProt P00747
Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa, higher selectivity than trypsin. Converts fibrin into soluble products.
-!- Formed from plasminogen by proteolysis which results in multiple forms of the active plasmin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.14.
|
UniProtKB Entries (2)
| P49054 |
PAM_STRPY
Streptococcus pyogenes
Plasminogen-binding group A streptococcal M-like protein PAM
|
| P00747 |
PLMN_HUMAN
Homo sapiens
Plasminogen
|
PDB Structure
| PDB | 1I5K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Pichia |
| Primary Citation |
Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein.
J.Mol.Biol.
|
