CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | UDP-glucose 4-epimerase |
Enzyme Information
| 5.1.3.7 |
UDP-N-acetylglucosamine 4-epimerase.
based on mapping to UniProt Q14376
UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine.
|
| 5.1.3.2 |
UDP-glucose 4-epimerase.
based on mapping to UniProt Q14376
UDP-alpha-D-glucose = UDP-alpha-D-galactose.
-!- Also acts on UDP-2-deoxyglucose.
|
UniProtKB Entries (1)
| Q14376 |
GALE_HUMAN
Homo sapiens
UDP-glucose 4-epimerase
|
PDB Structure
| PDB | 1I3L |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Pichia |
| Primary Citation |
Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase.
J.Biol.Chem.
|
