CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | protein-L-isoaspartate(D-aspartate) O-methyltransferase isoform X3 |
Enzyme Information
| 2.1.1.77 |
Protein-L-isoaspartate(D-aspartate) O-methyltransferase.
based on mapping to UniProt P22061
S-adenosyl-L-methionine + protein L-isoaspartate = S-adenosyl-L- homocysteine + protein L-isoaspartate alpha-methyl ester.
-!- D-aspartate (but not L-aspartate) residues in proteins can also act as acceptors. -!- Formerly EC 2.1.1.24.
|
UniProtKB Entries (1)
| P22061 |
PIMT_HUMAN
Homo sapiens
Protein-L-isoaspartate(D-aspartate) O-methyltransferase
|
PDB Structure
| PDB | 1I1N |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of human L-isoaspartyl-O-methyl-transferase with S-adenosyl homocysteine at 1.6-A resolution and modeling of an isoaspartyl-containing peptide at the active site.
Protein Sci.
|
