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1 keywords

CATH Domain 1hviB00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.70 Cathepsin D, subunit A; domain 1
Homologous Superfamily 2.40.70.10 Acid Proteases

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

O92139
O92139_9HIV1
Human immunodeficiency virus 1
Protease

PDB Structure

PDB 1HVI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease
Hosur, M.V., Bhat, T.N., Kempf, D., Baldwin, E.T., Liu, B., Gulnik, S., Wideburg, N.E., Norbeck, D.W., Appelt, K., Erickson, J.W.
J.Am.Chem.Soc.
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