CATH Domain 1he4A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	flavin reductase (NADPH)

Enzyme Information

1.5.1.30	Flavin reductase (NADPH). based on mapping to UniProt P30043 Reduced riboflavin + NADP(+) = riboflavin + NADPH. -!- The enzyme from Entamoeba histolytica reduces riboflavin and galactoflavin, and, more slowly, FMN and FAD. -!- NADH is oxidized more slowly than NADPH. -!- Formerly EC 1.6.8.2.
1.3.1.24	Biliverdin reductase. based on mapping to UniProt P30043 Bilirubin + NAD(P)(+) = biliverdin + NAD(P)H.

UniProtKB Entries (1)

BLVRB_HUMAN

Homo sapiens

Flavin reductase (NADPH)

PDB Structure

PDB	1HE4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme Pereira, P.J.B., Macedo-Ribeiro, S., Parraga, A., Perez-Luque, R., Cunningham, O., Darcy, K., Mantle, T.J., Coll, M. Nat.Struct.Biol.