CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.900 | Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A |
|
3.30.900.10 | HORMA domain |
Domain Context
CATH Clusters
| Superfamily | HORMA domain |
| Functional Family | Mitotic spindle assembly checkpoint protein MAD2A |
Enzyme Information
UniProtKB Entries (1)
| Q13257 |
MD2L1_HUMAN
Homo sapiens
Mitotic spindle assembly checkpoint protein MAD2A
|
PDB Structure
| PDB | 1GO4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint.
EMBO J.
|