CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.287 | Helix Hairpins |
|
1.10.287.110 | DnaJ domain |
Domain Context
CATH Clusters
| Superfamily | DnaJ domain |
| Functional Family | Small t antigen |
Enzyme Information
| 3.6.4.- |
Acting on ATP; involved in cellular and subcellular movement.
based on mapping to UniProt P03070
|
UniProtKB Entries (2)
| P03070 |
LT_SV40
Macaca mulatta polyomavirus 1
Large T antigen
|
| P06400 |
RB_HUMAN
Homo sapiens
Retinoblastoma-associated protein
|
PDB Structure
| PDB | 1GH6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen.
EMBO J.
|
