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1 keywords

CATH Domain 1fydB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.620 HUPs

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family NH(3)-dependent NAD(+) synthetase

Enzyme Information

6.3.1.5
NAD(+) synthase.
based on mapping to UniProt P08164
ATP + deamido-NAD(+) + NH(3) = AMP + diphosphate + NAD(+).
-!- L-glutamine also acts, more slowly, as amido-donor (cf. EC 6.3.5.1).

UniProtKB Entries (1)

P08164
NADE_BACSU
Bacillus subtilis subsp. subtilis str. 168
NH(3)-dependent NAD(+) synthetase

PDB Structure

PDB 1FYD
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Stabilization of active-site loops in NH3-dependent NAD+ synthetase from Bacillus subtilis.
Devedjiev, Y., Symersky, J., Singh, R., Jedrzejas, M., Brouillette, C., Brouillette, W., Muccio, D., Chattopadhyay, D., DeLucas, L.
Acta Crystallogr.,Sect.D
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