CATH Domain 1frfS01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.700	NADH:ubiquinone oxidoreductase-like, 20kDa subunit

Domain Context

CATH Clusters

Superfamily	NADH:ubiquinone oxidoreductase-like, 20kDa subunit
Functional Family

Enzyme Information

1.12.2.1

Cytochrome-c3 hydrogenase.

based on mapping to UniProt P18187

H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.

-!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). -!- Methylene blue and other acceptors can also be reduced.

UniProtKB Entries (1)

P18188

PHNL_DESFR

Desulfovibrio fructosivorans

Periplasmic [NiFe] hydrogenase large subunit

PDB Structure

PDB	1FRF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	3Fe-4S] to [4Fe-4S] cluster conversion in Desulfovibrio fructosovorans [NiFe] hydrogenase by site-directed mutagenesis Rousset, M., Montet, Y., Guigliarelli, B., Forget, N., Asso, M., Bertrand, P., Fontecilla-Camps, J.C., Hatchikian, E.C. Proc.Natl.Acad.Sci.USA