CATH Domain 1f5nA01

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1000	Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1
	1.20.1000.10	Guanylate-binding protein, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Guanylate-binding protein, C-terminal domain
Functional Family	Guanylate binding protein 1

Enzyme Information

3.6.5.-

Acting on GTP; involved in cellular and subcellular movement.

based on mapping to UniProt P32455

UniProtKB Entries (1)

GBP1_HUMAN

Homo sapiens

Guanylate-binding protein 1

PDB Structure

PDB	1F5N
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism. Prakash, B., Renault, L., Praefcke, G.J., Herrmann, C., Wittinghofer, A. EMBO J.