CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1260 | Ferritin |
|
1.20.1260.10 | Ferritin, core subunit, four-helix bundle |
Domain Context
CATH Clusters
| Superfamily | 1.20.1260.10 |
| Functional Family | Non-heme ferritin |
Enzyme Information
| 1.16.3.2 |
Bacterial non-heme ferritin.
based on mapping to UniProt P0A998
4 Fe(2+) + O(2) + 6 H(2)O = 4 (FeO(OH)) + 8 H(+).
-!- Ferritins are intracellular iron-storage and detoxification proteins found in all kingdoms of life. -!- They are formed from two subunits that co-assemble in various ratios to form a spherical protein shell. -!- Thousands of mineralized iron atoms are stored within the core of the structure. -!- The product of dioxygen reduction by the bacterial non-heme ferritin is hydrogen peroxide, which is consumed in a subsequent reaction.
|
UniProtKB Entries (1)
| P0A998 |
FTNA_ECOLI
Escherichia coli K-12
Bacterial non-heme ferritin
|
PDB Structure
| PDB | 1EUM |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The high-resolution X-ray crystallographic structure of the ferritin (EcFtnA) of Escherichia coli; comparison with human H ferritin (HuHF) and the structures of the Fe(3+) and Zn(2+) derivatives.
J.Mol.Biol.
|
