CATH Domain 1em1B01

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.287	Helix Hairpins
	1.10.287.990	Fe,Mn superoxide dismutase (SOD) domain

Domain Context

CATH Clusters

Superfamily	Fe,Mn superoxide dismutase (SOD) domain
Functional Family	Superoxide dismutase

Enzyme Information

1.15.1.1

Superoxide dismutase.

based on mapping to UniProt P04179

2 superoxide + 2 H(+) = O(2) + H(2)O(2).

UniProtKB Entries (1)

SODM_HUMAN

Homo sapiens

Superoxide dismutase [Mn], mitochondrial

PDB Structure

PDB	1EM1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Multiple replacements of glutamine 143 in human manganese superoxide dismutase: effects on structure, stability, and catalysis. Leveque, V.J., Stroupe, M.E., Lepock, J.R., Cabelli, D.E., Tainer, J.A., Nick, H.S., Silverman, D.N. Biochemistry