CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.720 | Alkaline Phosphatase, subunit A |
|
3.40.720.10 | Alkaline Phosphatase, subunit A |
Domain Context
CATH Clusters
| Superfamily | Alkaline Phosphatase, subunit A |
| Functional Family | Arylsulfatase A |
Enzyme Information
| 3.1.6.8 |
Cerebroside-sulfatase.
based on mapping to UniProt P15289
A cerebroside 3-sulfate + H(2)O = a cerebroside + sulfate.
-!- Hydrolyzes galactose-3-sulfate residues in a number of lipids. -!- Also hydrolyzes ascorbate 2-sulfate and many phenol sulfates.
|
UniProtKB Entries (1)
| P15289 |
ARSA_HUMAN
Homo sapiens
Arylsulfatase A
|
PDB Structure
| PDB | 1E33 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Defective oligomerization of arylsulfatase a as a cause of its instability in lysosomes and metachromatic leukodystrophy.
J. Biol. Chem.
|