CATH Domain 1dg3A01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1000	Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1
	1.20.1000.10	Guanylate-binding protein, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Guanylate-binding protein, C-terminal domain
Functional Family	Guanylate binding protein 1

Enzyme Information

3.6.5.-

Acting on GTP; involved in cellular and subcellular movement.

based on mapping to UniProt P32455

UniProtKB Entries (1)

GBP1_HUMAN

Homo sapiens

Guanylate-binding protein 1

PDB Structure

PDB	1DG3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins. Prakash, B., Praefcke, G.J., Renault, L., Wittinghofer, A., Herrmann, C. Nature