CATH Domain 1ajrB02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.640	Aspartate Aminotransferase; domain 2
	3.40.640.10	Type I PLP-dependent aspartate aminotransferase-like (Major domain)

Domain Context

CATH Clusters

Superfamily	Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family	Aspartate aminotransferase

Enzyme Information

2.6.1.3	Cysteine transaminase. based on mapping to UniProt P00503 L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate.
2.6.1.1	Aspartate transaminase. based on mapping to UniProt P00503 L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate. -!- Also acts on L-tyrosine, L-phenylalanine and L-tryptophan. -!- This activity can be formed from EC 2.6.1.57 by controlled proteolysis.

UniProtKB Entries (1)

AATC_PIG

Sus scrofa

Aspartate aminotransferase, cytoplasmic

PDB Structure

PDB	1AJR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Refinement and comparisons of the crystal structures of pig cytosolic aspartate aminotransferase and its complex with 2-methylaspartate. Rhee, S., Silva, M.M., Hyde, C.C., Rogers, P.H., Metzler, C.M., Metzler, D.E., Arnone, A. J.Biol.Chem.