CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family | Pheromone-processing carboxypeptidase KEX1 |
Enzyme Information
| 3.4.16.6 |
Carboxypeptidase D.
based on mapping to UniProt P09620
Preferential release of a C-terminal arginine or lysine residue.
-!- Carboxypeptidases of broad specificity with optimum pH 4.5-6.0, inhibited by the action of diisopropyl fluorophosphate, and sensitive to thiol-blocking reagents. -!- Belongs to peptidase family S10. -!- Formerly EC 3.4.12.1, EC 3.4.12.12, EC 3.4.16.1, EC 3.4.16.3 and EC 3.4.21.13.
|
UniProtKB Entries (1)
| P09620 |
KEX1_YEAST
Saccharomyces cerevisiae S288C
Pheromone-processing carboxypeptidase KEX1
|
PDB Structure
| PDB | 1AC5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of Kex1deltap, a prohormone-processing carboxypeptidase from Saccharomyces cerevisiae.
Biochemistry
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