Rationally Designed, Conformationally Constrained Inverse Agonists of ROR gamma t-Identification of a Potent, Selective Series with Biologic-Like in Vivo Efficacy.
Marcoux, D., Duan, J.J., Shi, Q., Cherney, R.J., Srivastava, A.S., Cornelius, L., Batt, D.G., Liu, Q., Beaudoin-Bertrand, M., Weigelt, C.A., Khandelwal, P., Vishwakrishnan, S., Selvakumar, K., Karmakar, A., Gupta, A.K., Basha, M., Ramlingam, S., Manjunath, N., Vanteru, S., Karmakar, S., Maddala, N., Vetrichelvan, M., Gupta, A., Rampulla, R.A., Mathur, A., Yip, S., Li, P., Wu, D.R., Khan, J., Ruzanov, M., Sack, J.S., Wang, J., Yarde, M., Cvijic, M.E., Li, S., Shuster, D.J., Borowski, V., Xie, J.H., McIntyre, K.W., Obermeier, M.T., Fura, A., Stefanski, K., Cornelius, G., Hynes Jr., J., Tino, J.A., Macor, J.E., Salter-Cid, L., Denton, R., Zhao, Q., Carter, P.H., Dhar, T.G.M.
J.Med.Chem.
