PDB Information

PDB6QBS
MethodX-RAY DIFFRACTION
Host OrganismKomagataella phaffii GS115
Gene SourceHomo sapiens
Primary Citation
The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K.
Mons, E., Jansen, I.D.C., Loboda, J., van Doodewaerd, B.R., Hermans, J., Verdoes, M., van Boeckel, C.A.A., van Veelen, P.A., Turk, B., Turk, D., Ovaa, H.
J. Am. Chem. Soc.
HeaderHydrolase
Released2018-12-21
Resolution1.700
CATH Insert Date10 Feb, 2019

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Feb, 2019 Chopped
B 10 Feb, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6qbsA00 11 Feb, 2019 3.90.70.10 Assigned
6qbsB00 11 Feb, 2019 3.90.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P43235 CATK_HUMAN Homo sapiens Cathepsin K
P43235 CATK_HUMAN Homo sapiens Cathepsin K
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