PDB 6pz4

PDB Information

PDB6PZ4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of AM-6494: A Potent and Orally Efficacious beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2.
Pettus, L.H., Bourbeau, M.P., Bradley, J., Bartberger, M.D., Chen, K., Hickman, D., Johnson, M., Liu, Q., Manning, J.R., Nanez, A., Siegmund, A.C., Wen, P.H., Whittington, D.A., Allen, J.R., Wood, S.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2019-07-31
Resolution1.850
CATH Insert Date27 Oct, 2019

PDB Images (1)

PDB Prints

PDB Chains (0)

Chain ID Date inserted into CATH CATH Status

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description