PDB Information

PDB6OVC
MethodSOLUTION NMR
Host OrganismEscherichia coli K-12
Gene SourceHomo sapiens
Primary Citation
AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies.
Caenepeel, S., Brown, S.P., Belmontes, B., Moody, G., Keegan, K.S., Chui, D., Whittington, D.A., Huang, X., Poppe, L., Cheng, A.C., Cardozo, M., Houze, J., Li, Y., Lucas, B., Paras, N.A., Wang, X., Taygerly, J.P., Vimolratana, M., Zancanella, M., Zhu, L., Cajulis, E., Osgood, T., Sun, J., Damon, L., Egan, R.K., Greninger, P., McClanaghan, J.D., Gong, J., Moujalled, D., Pomilio, G., Beltran, P., Benes, C.H., Roberts, A.W., Huang, D.C., Wei, A., Canon, J., Coxon, A., Hughes, P.E.
Cancer Discov
HeaderApoptosis/Inhibitor
Released2019-05-07
Resolution
CATH Insert Date26 May, 2019

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 26 May, 2019 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
6ovcA01 27 May, 2019 1.10.437.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
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