PDB Information

PDB6OMU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases.
Caldwell, R.D., Qiu, H., Askew, B.C., Bender, A.T., Brugger, N., Camps, M., Dhanabal, M., Dutt, V., Eichhorn, T., Gardberg, A.S., Goutopoulos, A., Grenningloh, R., Head, J., Healey, B., Hodous, B.L., Huck, B.R., Johnson, T.L., Jones, C., Jones, R.C., Mochalkin, I., Morandi, F., Nguyen, N., Meyring, M., Potnick, J.R., Santos, D.C., Schmidt, R., Sherer, B., Shutes, A., Urbahns, K., Follis, A.V., Wegener, A.A., Zimmerli, S.C., Liu-Bujalski, L.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2019-04-19
Resolution1.410
CATH Insert Date18 Aug, 2019

PDB Images (2)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 18 Aug, 2019 New

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description