Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK).
Watterson, S.H., Liu, Q., Beaudoin Bertrand, M., Batt, D.G., Li, L., Pattoli, M.A., Skala, S., Cheng, L., Obermeier, M.T., Moore, R., Yang, Z., Vickery, R., Elzinga, P.A., Discenza, L., D'Arienzo, C., Gillooly, K.M., Taylor, T.L., Pulicicchio, C., Zhang, Y., Heimrich, E., McIntyre, K.W., Ruan, Q., Westhouse, R.A., Catlett, I.M., Zheng, N., Chaudhry, C., Dai, J., Galella, M.A., Tebben, A.J., Pokross, M., Li, J., Zhao, R., Smith, D., Rampulla, R., Allentoff, A., Wallace, M.A., Mathur, A., Salter-Cid, L., Macor, J.E., Carter, P.H., Fura, A., Burke, J.R., Tino, J.A.
J. Med. Chem.
