PDB 6o2z

PDB Information

PDB6O2Z
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors.
Lin, J., Lu, W., Caravella, J.A., Campbell, A.M., Diebold, R.B., Ericsson, A., Fritzen, E., Gustafson, G.R., Lancia Jr., D.R., Shelekhin, T., Wang, Z., Castro, J., Clarke, A., Gotur, D., Josephine, H.R., Katz, M., Diep, H., Kershaw, M., Yao, L., Kauffman, G., Hubbs, S.E., Luke, G.P., Toms, A.V., Wang, L., Bair, K.W., Barr, K.J., Dinsmore, C., Walker, D., Ashwell, S.
J.Med.Chem.
HeaderOxidoreductase/Inhibitor
Released2019-02-25
Resolution2.500
CATH Insert Date07 Jul, 2019

PDB Images (3)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Jul, 2019 New
B 07 Jul, 2019 New

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description