PDB Information

PDB6NZF
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Identification ofN-Methyl Nicotinamide andN-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2).
Moslin, R., Zhang, Y., Wrobleski, S.T., Lin, S., Mertzman, M., Spergel, S., Tokarski, J.S., Strnad, J., Gillooly, K., McIntyre, K.W., Zupa-Fernandez, A., Cheng, L., Sun, H., Chaudhry, C., Huang, C., D'Arienzo, C., Heimrich, E., Yang, X., Muckelbauer, J.K., Chang, C., Tredup, J., Mulligan, D., Xie, D., Aranibar, N., Chiney, M., Burke, J.R., Lombardo, L., Carter, P.H., Weinstein, D.S.
J.Med.Chem.
HeaderTransferase
Released2019-02-13
Resolution2.390
CATH Insert Date04 Aug, 2019

PDB Images (3)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 04 Aug, 2019 New
B 04 Aug, 2019 New

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description
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