Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma.
Wang, X., Blackaby, W., Allen, V., Chan, G.K.Y., Chang, J.H., Chiang, P.C., Diene, C., Drummond, J., Do, S., Fan, E., Harstad, E.B., Hodges, A., Hu, H., Jia, W., Kofie, W., Kolesnikov, A., Lyssikatos, J.P., Ly, J., Matteucci, M., Moffat, J.G., Munugalavadla, V., Murray, J., Nash, D., Noland, C.L., Del Rosario, G., Ross, L., Rouse, C., Sharpe, A., Slaga, D., Sun, M., Tsui, V., Wallweber, H., Yu, S.F., Ebens, A.J.
J. Med. Chem.