PDB 6njh

PDB Links
Overview

PDB Information

PDB	6NJH
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders. Gurney, M.E., Nugent, R.A., Mo, X., Sindac, J.A., Hagen, T.J., Fox III, D., O'Donnell, J.M., Zhang, C., Xu, Y., Zhang, H.T., Groppi, V.E., Bailie, M., White, R.E., Romero, D.L., Vellekoop, A.S., Walker, J.R., Surman, M.D., Zhu, L., Campbell, R.F. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2019-01-03
Resolution	2.150
CATH Insert Date	12 May, 2019

PDB Images (9)

Image of CATH 6njh

6njh

PDB 6njh

Image of CATH 6njhA

6njhA

PDB Chain 6njhA

Image of CATH 6njhB

6njhB

PDB Chain 6njhB

Image of CATH 6njhC

6njhC

PDB Chain 6njhC

Image of CATH 6njhD

6njhD

PDB Chain 6njhD

Image of CATH 6njhA00

6njhA00

CATH Domain 6njhA00

Image of CATH 6njhB00

6njhB00

CATH Domain 6njhB00

Image of CATH 6njhC00

6njhC00

CATH Domain 6njhC00

Image of CATH 6njhD00

6njhD00

CATH Domain 6njhD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	12 May, 2019	Chopped
B	12 May, 2019	Chopped
C	12 May, 2019	Chopped
D	12 May, 2019	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6njhA00	13 May, 2019	1.10.1300.10	Assigned
6njhB00	13 May, 2019	1.10.1300.10	Assigned
6njhC00	13 May, 2019	1.10.1300.10	Assigned
6njhD00	13 May, 2019	1.10.1300.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D