PDB Information

PDB6NHE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceRattus norvegicus
Primary Citation
Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.
Do, H.T., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
HeaderOxidoreductase
Released2018-12-21
Resolution2.000
CATH Insert Date17 Mar, 2019

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2019 Chopped
B 17 Mar, 2019 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
6nheA01 18 Mar, 2019 3.90.340.10 Assigned
6nheA02 18 Mar, 2019 3.90.440.10 Assigned
6nheA03 18 Mar, 2019 3.90.1230.10 Assigned
6nheB01 18 Mar, 2019 3.90.340.10 Assigned
6nheB02 18 Mar, 2019 3.90.440.10 Assigned
6nheB03 18 Mar, 2019 3.90.1230.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P29476 NOS1_RAT Rattus norvegicus Nitric oxide synthase, brain
P29476 NOS1_RAT Rattus norvegicus Nitric oxide synthase, brain
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