PDB Information

PDB6NH0
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceRattus norvegicus
Primary Citation
Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.
Do, H.T., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2018-12-21
Resolution1.900
CATH Insert Date17 Mar, 2019

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2019 Chopped
B 17 Mar, 2019 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
6nh0A01 18 Mar, 2019 3.90.340.10 Assigned
6nh0A02 18 Mar, 2019 3.90.440.10 Assigned
6nh0A03 18 Mar, 2019 3.90.1230.10 Assigned
6nh0B01 18 Mar, 2019 3.90.340.10 Assigned
6nh0B02 18 Mar, 2019 3.90.440.10 Assigned
6nh0B03 18 Mar, 2019 3.90.1230.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P29476 NOS1_RAT Rattus norvegicus Nitric oxide synthase, brain
P29476 NOS1_RAT Rattus norvegicus Nitric oxide synthase, brain
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