PDB 6n4e

PDB Information

PDB6N4E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors.
Deaton, D.N., Do, Y., Holt, J., Jeune, M.R., Kramer, H.F., Larkin, A.L., Orband-Miller, L.A., Peckham, G.E., Poole, C., Price, D.J., Schaller, L.T., Shen, Y., Shewchuk, L.M., Stewart, E.L., Stuart, J.D., Thomson, S.A., Ward, P., Wilson, J.W., Xu, T., Guss, J.H., Musetti, C., Rendina, A.R., Affleck, K., Anders, D., Hancock, A.P., Hobbs, H., Hodgson, S.T., Hutchinson, J., Leveridge, M.V., Nicholls, H., Smith, I.E.D., Somers, D.O., Sneddon, H.F., Uddin, S., Cleasby, A., Mortenson, P.N., Richardson, C., Saxty, G.
Bioorg. Med. Chem.
HeaderHydrolase
Released2018-11-19
Resolution1.650
CATH Insert Date31 Mar, 2019

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 31 Mar, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6n4eA01 01 Apr, 2019 3.40.30.10 Assigned
6n4eA02 01 Apr, 2019 1.20.1050.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60760 HPGDS_HUMAN Homo sapiens Hematopoietic prostaglandin D synthase