PDB Information

PDB6MSA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Novel, potent, selective, and brain penetrant phosphodiesterase 10A inhibitors.
Geneste, H., Drescher, K., Jakob, C., Laplanche, L., Ochse, M., Torrent, M.
Bioorg. Med. Chem. Lett.
HeaderHydrolase
Released2018-10-16
Resolution2.060
CATH Insert Date20 Jan, 2019

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 20 Jan, 2019 Chopped
B 20 Jan, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6msaA00 21 Jan, 2019 1.10.1300.10 Assigned
6msaB00 21 Jan, 2019 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
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