PDB Information

PDB6MKK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
Trilles, R., Beglov, D., Chen, Q., He, H., Wireman, R., Reed, A., Chennamadhavuni, S., Panek, J.S., Brown, L.E., Vajda, S., Porco Jr., J.A., Kelley, M.R., Georgiadis, M.M.
J. Med. Chem.
HeaderLyase
Released2018-09-25
Resolution1.440
CATH Insert Date03 Feb, 2019

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Feb, 2019 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
6mkkA00 04 Feb, 2019 3.60.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P27695 APEX1_HUMAN Homo sapiens DNA-(apurinic or apyrimidinic site) lyase